Overview

Interphase Fluorescent in situ Hybridisation or FISH, is a technique use in the paediatric setting to provide rapid results for the detection of chromosomal trisomies like Down syndrome (trisomy 21). FISH may also be used for urgent microdeletion syndrome confirmation and to diagnose certain classes of paediatric cancers. Interphase FISH is a useful technique because it uses uncultured cells, meaning it can provide rapid test turn around times (usually within 24-48 hours).

Category

Cost

$196.35 (Medicare criteria apply)

Reporting time

Results available the next business day, if received before 3.00pm.

Contacts

Phone: 1300 11 8247
Email: [email protected]

Specimen Requirements

Lithium Heparin Blood (no gel)

Adults/Children: 5 ml

Infants: 1-2 ml

Neonates: 0.5-1 ml

Notes

Interphase FISH is always followed up with either a conventional karyotype or a molecular karyotype depending on the clinical indication and the FISH result obtained.

Storage Requirements: Do not freeze. Store at 4°C or room temperature.