Chimerism
Overview
Chimerism analysis is used after blood stem cell transplant to monitor the success of engraftment or to detect early graft failure, rejection and relapse. The test evaluates the mixture of donor and recipient DNA in the recipient’s blood or bone marrow.
Category
Cost
Please contact the laboratory
Contacts
Vida Petrovic and Jackie Challis
Phone (03) 8341 6280
Specimen Requirements
EDTA blood or bone marrow:
Less than 12 months of age: 1ml
Greater than 12 months: 5ml
For Chimerism analysis we require a pre transplant genotyping workup:
This requires samples from the pre transplant recipient and donor and;
samples from the post transplant recipient.
Flow sorted chimerism testing must be booked a week in advance